Abstract 20840: Feasibility of a Visualization Radio Frequency Balloon Catheter for Epicardial Ablation
Introduction: Epicardial ablation has been shown to improve VT outcomes, but is generally used after a failed attempt of endocardial ablation. The potential of injuring epicardial coronary arteries and the phrenic nerve have hindered epicardial VT ablation. To address these challenges, a radio frequency (RF) multi-electrode balloon with visualization capability was developed and tested in a porcine model.
Hypothesis: Use of radio frequency balloon with visualization will improve safety and efficacy of epicardial ablation
Methods: Yorkshire porcine hearts were used to define power and duration settings to produce consistent RF lesions. For in vivo studies, the catheter was delivered over-the-wire through a steerable sheath within the pericardial space. The inter-balloon image provided verification of the electrode position and contact to the tissue, while avoiding coronary arteries. Electrodes were selected for bipolar ablation of the ventricle. Cardiac tissue was examined grossly and then incubated in triphenyl tetrazolium chloride (TTC) dye. Ablations and surrounding structures were examined post-staining.
Results: Consistent ablation lesions were made with depths ranging from 3.7 mm to 5.8 mm that was dependent on power and duration of lesion creation. Conformation of tissue contact was verified with cameras mounted within the balloon, as well as detection of coronary arteries. RF lesions were between 5-6 mm depth.
Conclusions: The multi-electrode RF balloon catheter produced reliable epicardial lesion. The direct visualization within the balloon provides optimization of lesion placement and avoidance of coronary arteries.
Author Disclosures: N. Badhwar: Honoraria; Modest; Boeringer Ingelhiem. A. Al-Ahmad: None. M. Rippy: None. V. Reddy: None. G. Narayan: None. K. Heinz Kuck: None. I. Crozier: None. M. Daly: None. I. Melton: None. T.E. Walters: None. R.J. Lee: Ownership Interest; Modest; Apama. Consultant/Advisory Board; Modest; Apama. B. Lee: None. B. Lee: None.
- © 2016 by American Heart Association, Inc.