Abstract 20618: Comparison of In-Hospital Outcomes Among HIV Seropositive versus HIV Seronegative Patients Admitted With Heart Failure in the United States: 2000 to 2012
Introduction: Cardiovascular disease is a major cause of morbidity and mortality in the Human Immunodeficiency Virus (HIV) positive population. Limited data exists comparing the clinical outcomes between HIV positive and negative patients admitted for heart failure (HF).
Methods: Patients with a primary diagnosis of HF were identified from the Nationwide Inpatient Sample (NIS) database from 2000 to 2012. The cohort was divided into HIV positive and negative groups. Demographic and clinical parameters were obtained using the International Classification of Diseases, Ninth Revision, Clinical Modification (ICD-9-CM) codes. Descriptive and multivariate analyses were done using SPSS Version 24.
Results: Of the 639,947 HF patients, 2212 were HIV positive. HIV positive patients were younger (54±11 vs.73±14, p<0.001), predominantly male (67% vs.48.3%, p<0.001), had higher rates of end stage renal disease (17.5% vs.4.7%, p<0.001), and significantly lower rates of diabetes mellitus (DM), hypertension (HTN) and coronary artery disease (CAD) as compared to the HIV negative patients. The HIV positive cohort had a higher prevalence of systolic HF (59.1% vs.45.5% p< 0.001), and underwent more automated implantable cardioverter defibrillator (AICD) implantations (1.6% vs.1.0%, p<0.006). The HIV positive cohort had a significantly higher inpatient cost burden and length of stay (LOS). Univariate analysis revealed HIV positive patients had lower rates of in-hospital mortality (1.5% vs.2.7%, p<0.001); however, when adjusted for various co-morbidities on multivariate analysis, HIV positive status was not an independent predictor of inpatient mortality.
Conclusions: Between 2000 and 2012, HIV positive status was associated with a higher inpatient cost and LOS among patients admitted for HF. Despite the HIV positive cohort being younger and with overall fewer cardiovascular co-morbidities, no significant difference was found in HF related inpatient mortality.
Author Disclosures: N. Mathenge: None. M. Patel: None. S. Dikdan: None. A. Kazi: None. M. Kinno: None. E. Rashed: None. R. Banerjee: None. K. Moazzami: None. O. Onibile: None. A. Waller: None. M. Klapholz: None.
- © 2016 by American Heart Association, Inc.