Abstract 20416: Hospital Admissions for Acute Myocardial Infarctions in HIV Patients
Introduction/Hypothesis: Infection with the human immunodeficiency virus (HIV) has been found to be a risk factor for the development of early and more extensive coronary artery disease. Data examining the epidemiology of its cardiovascular and social implications are lacking.
Methods: Data was collected from the Nationwide Inpatient Sample (NIS) between 2002 and 2012. Subjects were identified using the International Classification of Diseases, 9th Revision Clinical Modification (ICD-9-CM) codes.
Results: We identified a total of 4822patients with HIV admitted for acute myocardial infarction from 2001 to 2012. During the first half of the decade, the number of admissions dwindled, but steadily increased during the second half. Most patients were male (81.1%) with a mean age of51.8± 9.5 years. Over half the patients belonged to the lowest two income quartile and had average Charlson’s comorbidity score of 4.97. Most patients presented to large, urban institutions in the south of the US. Total of 1608 patients underwent stent placement. Overall, throughout these years, the use of drug eluting stents (DES) increased to a cumulative average of 19.7%. The use of bare metal stents (BMS), initially decreased over the first five years and later increased to a cumulative average of 13.6%. There was no statistically significantdifference in the use of BMS and DES (0.85% vs 0.85%, p=0.998), mortality related to type of stent received (14.66% vs 11.71, p=0.267), or vascular complications (0.63%, 0.63%, p=1). Median duration of hospital stay was 5 days and in-hospital mortality was 4.64%.
Conclusions: Acute myocardial infarction is associated with significant mortality in the HIV population. The use of DES has increased over the years, whereas the use of BMS initially decreased but has once again resurged. Nonetheless, over half of the patients did not receive any stent placement. Further studies should be conducted to elucidate whether particular angiographic findings inherent to this population are responsible for this apparent disparity.
Author Disclosures: G.T. Savani: None. P. Bhatt: None. V. Singh: None. A.P. Rodriguez: None. N.J. Patel: None. B. Thakkar: None. V. Blumer: None. M. Rivera: None. R. Mendirichaga: None. V. Singh: None. F. Patel: None. C. Alfonso: None. M.G. Cohen: None.
- © 2016 by American Heart Association, Inc.