Abstract 20257: Decline in Chest Compression Release Velocity Over Time is Associated With Out-of-Hospital Cardiac Arrest Outcomes
Background: High chest compression release velocity (CCRV) has been independently associated with improved outcomes after out-of-hospital cardiac arrest (OHCA). We assessed the change in CCRV over time during resuscitation and its association with patient outcomes.
Methods: CCRV was measured using an accelerometer connected to a defibrillator (E/X Series, ZOLL Medical) during adult OHCA resuscitations from 2 EMS agencies in Arizona between 10/2008 and 06/2015. All subjects had at least 20 compressions and compression duration of at least 1 minute within the first 10 minutes of resuscitation. Mean CCRV was summarized for the first and second 5-minute intervals and the rate of change in CCRV between intervals was estimated via linear regression. Patient-level mean and rate of change were summarized within each subgroup by the median and interquartile range, and were compared across subgroups by the Kruskal-Wallis test. All tests were two-sided with significance level of 0.05.
Results: A total of 1,308 subjects were included. For each subject, the median number of compressions was 785 and median compression duration was 519 seconds. CCRV was significantly higher during minutes 0-5 in patients with survival to hospital discharge compared to non-survivors and in patients with favorable (CPC=1 or 2) compared to unfavorable neurological outcome (Table). CCRV remained significantly higher for survivors compared to non-survivors in minutes 5-10 but was similar for neurological outcome. The decline in CCRV was greater in patients with survival to discharge, favorable neurological outcome, and ROSC.
Conclusion: CCRV was highest throughout the first 10 minutes of resuscitation for both survivors and those with and favorable neurological outcome. The rate of decline in CCRV was greater for patients with positive outcomes, possibly due to significantly higher CCRV in minutes 0-5.
Author Disclosures: S. Beger: None. J. Sutter: None. C. Hu: None. D.W. Spaite: Research Grant; Significant; Medtronic Foundation. A. Silver: None. R. McDannold: None. M. Mullins: None. T.F. Vadeboncoeur: None. B.J. Bobrow: Research Grant; Significant; Medtronic Foundation.
- © 2016 by American Heart Association, Inc.