Abstract 19419: Novel Remodeling Mitral Annuloplasty Ring That Preserves Axial Dynamics of the Native Mitral Annulus
Introduction: The design of mitral annuloplasty rings has evolved over the last decades with the introduction of flexible and semi-rigid rings. The rings have been developed to restore systolic saddle shaped annulus configuration while allowing mitral annular motion in specific directions. Despite acceptable results with annuloplasty rings there is still a need for innovations of annuloplasty devices that ensures a competent valve and maintains the natural out-of-annular-plane dynamics. In this study we tested a prototype of a novel remodeling annuloplasty ring with built-in septal-lateral annular fixation and commissural axial flexibility. The aim was to evaluate the biomechanical performance of the new remodeling annuloplasty ring compared to two common commercially available remodeling annuloplasty rings.
Methods: The measurements were performed in-vivo in an 80 kg porcine model. 28 animals were randomized evenly in four groups: A No ring, a novel remodeling ring, a semi-rigid ring (CE Physio ITM Ring) and a rigid ring group (CE ClassicTM Annuloplasty Ring). 3D dynamical geometry was measured with implanted sonomicrometry crystals.
Results: The novel remodeling, rigid and semi-rigid mitral annuloplasty rings equally restricted the annular geometry compared to the native valve (Figure, top). The mitral annular height of the semi-rigid and rigid rings was significantly lower in its maximum value and cyclic changes compared to the no ring group (Figure, bottom).
Conclusion: There were no differences in annular height between the novel remodeling ring and the native valve, indicating that the intended function of the new device was obtained. The annular systolic saddle shape is believed to protect the mitral valve function and decrease leaflet stresses. This new concept for a remodeling annuloplasty ring with integrated septal-lateral annular fixation and apical flexibility is unique and could be an important step towards improved mitral valve reconstruction.
Author Disclosures: S.N. Skov: None. D.M. Røpcke: None. M.J. Tjørnild: None. C. Ilkjær: None. J. Rasmussen: None. H. Nygaard: None. J.M. Hasenkam: None. M.O. Jensen: None. S.L. Nielsen: None.
- © 2016 by American Heart Association, Inc.