Abstract 19168: Lesion Characteristics Using a Novel Multi-Electrode Radiofrequency Balloon Ablation Catheter
Introduction: Conventional pulmonary vein (PV) isolation for atrial fibrillation (AF) is achieved with point-by-point radiofrequency (RF) ablation which has challenges. To address these challenges, we evaluated a novel multi-electrode RF balloon catheter (Apama, Inc., Campbell, CA) that has irrigated electrodes on the surface of the balloon which both map and ablate, and real-time visualization of electrode contact and lesion formation.
Hypothesis: We tested this novel catheter in animals to characterize lesion formation with the goal of transmural lesions.
Methods: In five (5) Yorkshire pigs, the novel balloon catheter was delivered over-the-wire through a steerable sheath to the left atrium. The camera within the balloon provided verification of the electrode position and apposition to tissue. Bipolar ablation was delivered via selected electrodes at the antrum of targeted pulmonary veins. Ablation lesions and surrounding structures were examined post-staining.
Results: In five (5) pigs treated, ablation lesions were all transmural, 1-5mm in depth. No endocardial thrombus or complications were observed. Surrounding structures including the lungs had no collateral damage.
Conclusion: Transmural lesions encircling the PVs were achieved using the multi-electrode RF balloon ablation catheter. Real time visualization provided direct feedback on electrode apposition, allowing immediate balloon adjustment without excessive manipulation. From this initial experience, human application of this technology is underway.
Author Disclosures: B.K. Lee: None. A. Al-Ahmad: None. M. Rippy: None. V. Reddy: None. G. Narayan: None. K. Kuck: None. I. Crozier: None. M. Daly: None. I. Melton: None. T.E. Walters: None. R.J. Lee: None. N. Badhwar: None.
- © 2016 by American Heart Association, Inc.