Abstract 18956: Comparison of Global and Regional Myocardial Strains in Patients With Heart Failure With a Preserved Ejection Fraction vs Hypertension vs Age Matched Control
Introduction, Hypothesis: The objective of this study was to analyze global and regional left ventricular (LV) strains using echocardiography speckle tracking in patients with HFpEF and compared those parameters with that of patients with hypertension and normal subjects.
Methods: Each regional and global longitudinal, circumferential and radial strains were evaluated with echocardiography using speckle-tracking for fifty patients with HFpEF, fifty-six patients with hypertension and forty-six age-matched normal subjects. Diastolic strain rate was also determined.
Results: Peak longitudinal, circumferential and radial strains and strain rate were globally reduced in patients with HFpEF compared to both hypertension patients and normal controls. In addition, the HFpEF patients demonstrated significantly lower longitudinal, circumferential and radial regional strain compared to both hypertension patients and normal controls, in all segments except in inferoseptal and inferolateral apical segments. Notably, global and regional strains and strain rate were significantly reduced in hypertension patients compared to normal subjects.
Conclusions: In the speckle-tracking echocardiography, impaired peak global strains and homogeneously reduced regional strains were observed in HFpEF patients compared to the hypertension patients and normal subjects, in decreasing order. This can provide additional information on the pathogenesis of HFpEF by demonstrating different magnitude of LV deformation among patients with HFpEF, hypertension and normal subjects.
Author Disclosures: H. Kim: None. S. Park: None. S. Lee: None. S. Jang: None. M. Park: None. E. Kim: None. S. Chang: None. J. Choi: None. S. Park: None. S. Kim: None. Y. Choe: None. J. Oh: None.
- © 2016 by American Heart Association, Inc.