Abstract 18159: Association Between Ankle-Brachial Index Values, Symptom Classification, and PAD-Specific Health Status in Patients With Intermittent Claudication
Introduction: The association between ankle brachial index (ABI) values and patients’ perceptions of their health status is poorly characterized. In the PORTRAIT study of patients with new or an exacerbation of intermittent claudication (IC) symptoms, we compared patients’ ABI and Rutherford symptom classification with their PAD-specific health status.
Methods: A total of 1,252 patients with new or worsening IC were enrolled at 17 PAD clinics in the US, the Netherlands, and Australia. Baseline demographic, socio-economic, psychological and clinical characteristics were recorded from medical records, and the Peripheral Artery Questionnaire (PAQ) was completed by patients. ABI values were categorized as mild (>0.80), moderate (0.40-0.79) and severe (<0.40), and a standard Rutherford symptom classification was used. Correlations between ABI and PAQ scores (summary, quality of life [QOL], symptoms, and physical limitations scores) and Rutherford category and PAQ Scores were assessed using Spearman’s rank correlation (all values were assessed as continuous variables).
Results: The median ABI was 0.67; 24.3% had a mildly, 67.7% moderately, and 8.0% severely impaired ABI. When compared with patients who had higher ABI values, patients with lower ABI values had a higher Rutherford classification and lower PAQ scores [Table]. ABI values did not correlate well with PAQ scores (PAQ summary, R=0.09; PAQ QOL, R=0.032; PAQ symptoms, R=0.044; PAQ physical limitations, R=0.14). Rutherford classification had a weak correlation with PAQ scores (PAQ summary, R= -0.27; PAQ QOL, R= -0.21; PAQ symptoms, R= -0.18; PAQ physical limitations, R=-0.27).
Conclusions: In a large cohort of patients presenting with IC at PAD specialty clinics, there was not a strong association between either ABI values or Rutherford classification with PAD-specific health status. These findings highlight that ABI alone does not capture the impact of PAD on patients’ PAD-specific health status.
Author Disclosures: A. Johnston: None. W. Jones: None. K. Gosch: Research Grant; Significant; Patient-Centered Outcomes Research Institute. M. Patel: None. S. Vemulapalli: None. H. Aronow: None. D. Abbott: None. M. Shishebor: None. J. Spertus: Research Grant; Significant; Patient-Centered Outcomes Research Institute. K. Smolderen: Research Grant; Significant; Patient-Centered Outcomes Research Institute.
- © 2016 by American Heart Association, Inc.