Abstract 17334: Mediterranean Diet But Not DASH Diet and AHEI Score is Associated With Lower Risk of Heart Failure in the Physicians’ Health Study
Introduction: Dietary patterns including Mediterranean (MED), Dietary Approach to Stop Hypertension (DASH), and Alternative Healthy Eating Index (AHEI) have shown to be associated with lower risk of cardiovascular disease and mortality. However, studies on dietary patterns and incident risk of HF are limited. Furthermore, it is unknown whether these diet patterns are associated with lower risk of heart failure among physicians who may already have optimal risk profile.
Hypothesis: Our primary hypothesis is that healthy dietary patterns are inversely associated with a lower risk of heart failure.
Methods: We prospectively analyzed data on 12,657 US male physicians who provided data on their dietary habits between 1997-2001 using food frequency questionnaires. Physicians with a history of heart failure, atrial fibrillation, and coronary heart disease were excluded from this analysis. Incident heart failure was ascertained through annual questionnaires with a validation in a subsample using review of medical records. Cox proportional hazard models were used to estimate hazard ratios.
Results: At baseline, average age was 64.7 ± 8.6 years. After average follow up of 9.8 years, 348 cases of incident heart failure occurred. MED score was inversely associated with the incidence of heart failure: hazard ratios (95%CI) of incident heart failure from lowest to highest quintile for MED diet were 1.0 (reference), 0.71 (0.51-0.99), 0.72 (0.52-0.98), 0.62 (0.44-0.87), and 0.83 (0.60-1.15), after adjusting age, smoking, exercise, and energy intake (p for linear trend 0.046, Table1). DASH and AHEI scores were not associated with the incidence of heart failure (Table1).
Conclusions: Within this cohort of male physicians, higher MED score, but not DASH and AHEI scores, was associated with a lower risk of heart failure.
Author Disclosures: Y. Patel: None. H. Shin: None. J.M. Gaziano: None. L. Djousse: None.
- © 2016 by American Heart Association, Inc.