Abstract 16321: Is Atrial Strain Just a Mirror Image of Ventricular Strain?
Introduction: Traditional difficulties with measurement of atrial function may have been addressed by development of atrial strain. Atrial mechanics may be involved in the pathogenesis of atrial fibrillation.
Hypothesis: Atrial pump function but not conduit function is independent of left ventricular (LV) mechanics.
Methods: In a community-based study of 576 pts (age 70.7±4.7 yrs, male 46%), participants ≥65 years were recruited if they had 1 or more risk factors (eg. hypertension, diabetes mellitus, obesity). Baseline echo was undertaken in all pts and LV/atrial strain analysis was conducted using a dedicated software package (Image Arena, Tomtec, Germany). Atrial strain analysis was performed using R-R gating. Patients were grouped according to global longitudinal strain (GLS) (≤ or > than the cut-off -18%) and global circumferential strain (GCS) (≤ or > than the cut-off -22%). The associations between GLS/GCS and atrial reservoir/conduit/pump strain were assessed using univariable and multivariable linear regression.
Results: Pts with reduced GLS had higher blood pressure and rates of diabetes mellitus (DM) and obesity (p<0.05). Atrial reservoir strain and conduit strain was lower in the reduced GLS group (38.2±7.3 vs. 39.9±6.4% p=0.004) and (18.7±5.7 vs. 20.5±5.1,p<0.001) however there was no significant difference in atrial pump strain (19.5±5.5 vs. 19.3±4.6,p=0.72). Pts with reduced GCS had a larger body mass index, were more likely male and had higher rates of DM (p<0.05). There was no significant differences in atrial reservoir, conduit and pump strain in pts with normal and abnormal GCS (p>0.05). GCS was not associated with atrial strain. GLS was independently associated with atrial reservoir and conduit strain (p<0.05), but not independently associated with atrial pump strain (p=0.91). (Table).
Conclusion: Atrial pump strain is independent of LV mechanics.
Author Disclosures: S. Ramkumar: None. H. Yang: None. Y. Wang: None. M. Nolan: None. K. Negishi: None. T.H. Marwick: None.
- © 2016 by American Heart Association, Inc.