Abstract 16190: Incidence and Outcomes of Patients Hospitalized With Myocardial Infarction and Co-existing Cerebrovascular Accident in United States
Introduction: Patients with myocardial infarction (MI) are at a higher risk of both ischemic and hemorrhagic cerebrovascular accidents (CVA). Data regarding trends and outcomes of patients hospitalized with MI and coexisting CVA remain scant.
Hypothesis: Patients with MI with coexisting CVA have higher length and cost of hospitalization and higher in-hospital mortality compared to those without CVA.
Methods: We assessed the incidence, trends and outcomes in patients with MI who had a CVA and compared this to patients with MI who did not have a CVA by utilizing nationwide inpatient sample database. Individual trends and outcomes of subarachnoid hemorrhage (SAH), hemorrhagic stroke (HS) and ischemic stroke (IS) were also assessed in patients with MI.
Results: A total of 550,849 patients with a diagnosis of myocardial infarction were included in the analysis, out of which 84,981 patients had a coexisting diagnosis of CVA. The number of patients with coexisting MI and CVA increased significantly from 2005 to 2012 (10% vs 20%, p<0.001). This was mostly driven by an increase in IS which almost doubled from 2005 to 2012 (9.8% vs 19.0%, p<0.001). Patients with coexisting MI and CVA had significantly increased length of stay (11.1 vs 8.3 days, p <0.001), cost of hospitalization ($99,069 vs $70,229, p<0.001) and in-hospital mortality (OR 1.6, p<0.001) when compared to MI patients without CVA. SAH was associated with highest risk of in-hospital mortality (Odds ratio (OR) for SAH 5.0, p<0.001; OR for HS 3.3, p<0.001; OR for IS 1.3, p<0.001).
Conclusion: The rates of CVA in patients with MI have increased significantly in the United States. CVA is associated with a longer and costlier hospital stay and a higher in-hospital mortality in patients with MI.
Author Disclosures: S. Aggarwal: None. R.S. Loomba: None. G. Aggarwal: None. N. Gupta: None. M. Kaushik: None. A. Mooss: None. M. White: None. R. Arora: None. V. Alla: None.
- © 2016 by American Heart Association, Inc.