Abstract 15782: Heart Failure Following Myocardial Infarction: Risk Factors and Trends in Incidence
Introduction: Application of new therapeutic modalities have resulted in a decrease in the mortality rate following myocardial infarction (MI), but heart failure (HF) remains a frequent complication. Published studies on the associations and incidence of HF after infarction have been contradictory with some reporting increasing and others decreasing incidence.
Methods: To examine trends in the incidence and predictors of HF after MI, we used data from the Myocardial Data Acquisition System (MIDAS), a statewide database including all non-federal admissions for myocardial infarction in the state of New Jersey. We assessed the incidence of HF after acute MI over time and the associations with demographics, comorbidities, and risk factors.
Results: From 2000 to 2011, 10,361 (10.59%) patients were admitted for HF within 1 year following the diagnosis of acute MI among 97,839 MI patients. Overall, the rate of admission for HF after MI ranged from 5.27% within 30 days of MI to 7.33% at 90 days, to 8.75% at 180 days, to 10.59% at 1 year. A secular decrease in each of these rates was observed over the time period studied. Logistic regression identified age (p<0.001), earlier discharge year (p<0.001), history of prior HF (p<0.001), history of hypertension (p=0.020), history of diabetes (p<0.001), and acute renal failure (p<0.001) as predictors of admission for HF within 1 year after a first MI.
Conclusions: The incidence of HF after acute MI has decreased over time and is correlated with older age, diabetes, kidney disease, and hypertension.
Author Disclosures: J. Wellings: None. D. Sargsyan: None. J.B. Kostis: Research Grant; Modest; Bayer, Boehringer Ingelheim. Research Grant; Significant; Novartis, Pfizer, Sanofi, AstraZeneca. Expert Witness; Modest; Vasios, Kelly & Strollo, PA, La Follette, Johnson De Haas, Fesler & Ames. Consultant/Advisory Board; Modest; ACI Clinical, Merck. Consultant/Advisory Board; Significant; Palatin, St. Jude Medical. J.M. Dobrzynski: None. W.J. Kostis: None.
- © 2016 by American Heart Association, Inc.