Abstract 14711: Circannual Pattern and TEMPerature-Related Incidence of Electrical STorm: The TEMPEST Study
Introduction: The occurrence of ventricular tachyarrhythmias appears to follow circadian, daily, and seasonal distributions. Identifying potential temporal pattern could be even more important in patients experiencing electrical storm (ES), in which a cluster of ventricular tachycardias (VTs) or ventricular fibrillation (VFs), negatively affects short- and long-term survival.
Hypothesis: ES incidence could be associated with the time of the year, time of the week, time of the day and short-term temperature variations.
Methods: The Circannual pattern and TEMPerature-related incidence of Electrical Storm study (TEMPEST, # CRD42013003744) is a patient-level meta-analysis. Study selection criteria included: diagnosis of ES; absence of acute coronary syndrome as the arrhythmic trigger; ten or more patients included. At the end of the selection and collection processes, 5 centres had the dataset from their papers merged into the registry. Temperature data and sunrise and sunset hours were retrieved from Weather Underground, the biggest weather database available online.
Results: A total of 246 patients admitted for ES (221 males, age 66±9 years) were enrolled. Each ES episode was made up by a median of 7 VT/VF episodes. Fifty-nine percent of patients experienced ES during daytime hours (p<0.001). Similarly, the incidence of ES was significantly more prevalent during work-days, with Saturdays and Sundays registering the lowest prevalence of ES (10.4 and 7.2% respectively, vs 16.5% daily mean from Monday to Friday; p<0.001). ES prevalence was homogenously distributed across the 12 months. ES incidence was significantly associated with an increase in the monthly temperature range when compared to the month before (p=0.003).
Conclusions: ES incidence is not homogenous over time but seems to recognize a clustered or “hot-spot” pattern, with a higher incidence during daytime hours and working days. ES is associated with an increase in monthly temperature range.
- Ventricular tachycardia
- Ventricular arrhythmia
- Implantable cardiovertor defibrillator
- Ventricular fibrillation
- Arrhythmias, treatment of
Author Disclosures: F. Guerra: None. P. Bonelli: None. M. Flori: None. L. Cipolletta: None. C. Carbucicchio: None. M. Izquierdo: None. E. Kozluk: None. M. Vaseghi: None. K. Shivkumar: None. F. Patani: None. C. Cupido: None. S. Pala: None. R. Luiz-Granell: None. A. Ferrero: None. C. Tondo: None. A. Capucci: None.
- © 2016 by American Heart Association, Inc.