Abstract 14315: Sex Differences in the Initial Management of Atrial Fibrillation and its Effect on the Patient’s Perception
Introduction: Although improvement in quality of life (QoL) is an important goal in the management of atrial fibrillation (AF), few contemporary data exist on the evaluation of patient’s perception according to patient sex.
Methods: A total of 1,284 newly treated AF patients (358 [27.8%] women) registered in Japanese multicenter outpatient-based database were evaluated. The registered patients answered a validated QoL questionnaire (Atrial Fibrillation Effect on QualiTy-of-life: AFEQT) at the time of enrollment; a higher score from each domain reflects a higher QoL. The QoL score was obtained 29 days(median) after the patients’ initial visit.
Results: The mean population age was 65.8 ± 11.7, the mean BMI was 23.6±3.5. Women were more likely to have history of congestive heart failure (19.0% vs 13.5%, p=0.013) and higher CHADS2 score (1.52 ±1.35 vs 1.17 ±1.14, p<0.0001), but application of oral anticoagulants was similar (81.0% vs 79.5%, p=0.541). During their initial management, women had lower AFEQT scores compared with men: 71.9 ±17.61 vs. 77.5 ± 16.6 (p<0.001), and similar trend were shown in individual domains (symptom, daily activities, and treatment concern). (Key Figure). Despite this lower AFEQT score in each of its domain, there were no sex differences in the use of anti-arrhythmic agent (21.8% vs 26.7%, p=0.071). Moreover, women were less likely to be treated with rhythm control strategy, including catheter ablation, than men (49.2% vs 59.7%, p<0.001).
Conclusions: The clinical characteristics of AF, as well as patients’ perception varied according to patient sex. Women have more comorbidities and worse overall QoL score than men, but tended to receive less aggressive treatments. Physicians need to recognize these difference in AF patients to optimize their care.
Author Disclosures: N. Ikemura: None. S. Kohsaka: None. T. Kimura: None. Y. Katsumata: None. T. Nishiyama: None. N. Nishiyama: None. K. Tanimoto: None. Y. Momiyama: None. M. Akaishi: None. H. Mitamura: None. S. Takatsuki: None. K. Fukuda: None.
- © 2016 by American Heart Association, Inc.