Abstract 14233: A Simple Risk Stratification Model for Acute Myocardial Infarction using the Combination of Blood Examination: Acute Myocardial Infarction-Kyoto Multi-Center Risk Study Group
Background: Acute myocardial infarction (AMI) is a disease associated with poor in-hospital prognosis. Although the thrombolysis in myocardial infarction (TIMI) risk score and TIMI risk index could predict AMI prognosis, these scoring tools seem to be insufficient for clinical use. Simply and rapidly evaluation model for AMI prognosis is preferable.
Methods: We developed a simple stratification model from the combination of blood examination in the derivation set (n = 1333) of AMI-Kyoto registry and assessed the utility of this model for the prediction of in-hospital mortality in the validation set (n = 647).
Results: We selected the following five variables which are factors reported to significantly worsen in-hospital mortality: white blood cell count, hemoglobin, C-reactive protein, Creatinine, and blood sugar levels. In the derivation set, each of the five variables significantly worsened in-hospital mortality. We developed the risk stratification model by the combination of these variables that were scored based on each beta coefficient obtained from multivariate analysis. We could found a significant trend of in-hospital mortality rate according to the total point of this laboratory stratification model. Therefore, we assessed the utility of this risk stratification model in our validation set. This risk stratification model could predict the in-hospital mortality in the validation set. In addition, in-hospital mortality rate assessed by the TIMI risk index could be predicted more effectively by subdivision using the laboratory risk stratification model.
Conclusions: This laboratory stratification model could simply and rapidly predict in-hospital mortality for AMI and could be useful for the detailed prediction of in-hospital mortality by subdividing the TIMI risk index.
Author Disclosures: K. Yanishi: None. T. Nakamura: None. N. Nakanishi: None. K. Zen: None. T. Yamano: None. H. Shiraishi: None. T. Shirayama: None. S. Matoba: None.
- © 2016 by American Heart Association, Inc.