Abstract 13966: Catheter Ablation for Atrial Fibrillation Reduces the Recurrence of Ischemic Stroke
Introduction: Cardioembolic stroke related to atrial fibrillation (AF) is associated with a high recurrence rate and high mortality and morbidity. Catheter ablation for AF is effective in reducing AF burden, while the impact of AF ablation on a recurrence of stroke remains to be elucidated.
Methods: We performed a retrospective multicenter cohort study of patients who were diagnosed with AF. A total of 1792 patients with AF (age 67±10, male 67%, 47% paroxysmal AF) were analyzed. Six hundred thirty-three patients underwent AF ablation. Patients with a history of transient ischemic attack (TIA) or ischemic stroke (IS) were listed. The association between a recurrence of TIA/IS, and AF ablation was evaluated.
Results: There were 282 patients with a history of TIA/IS (104 ablation, 178 no-ablation). Ablation group had more patients with heart failure than no-ablation group. Besides this, there were similar about CHADS2 score in both group. Fifty-six recurrences were observed. AF ablation was associated with a lower incidence of recurrences (Hazard ratio 0.30; 95% CI 0.11 - 0.85; p=0.02). Independent predictors of recurrences of TIA/IS were, not undergoing AF ablation, aging, and a presence of hypertension.
Conclusion: Our results suggested that AF ablation could reduce the recurrence of TIA/IS.
Author Disclosures: Y. Hama: None. M. Ishimura: None. T. Kuwahara: None. M. Ueda: None. A. Miyazaki: None. M. Yamanouchi: None. J. Kanda: None. M. Yamamoto: None. T. Himi: None. Y. Kobayashi: None.
- © 2016 by American Heart Association, Inc.