Abstract 13419: Linear Fractional Shortening on Echocardiography (Echo)- A Novel Index of Right Ventricular Systolic Dysfunction as Validated by Cardiac Magnetic Resonance (CMR)
Introduction: Among pts with LV systolic dysfunction (LVdys), biventricular (LV and RV) dysfunction (BiVdys) impacts outcomes. Echo linear indices are widely used to assess LVdys but performance for RVdys is unknown.
Methods: The population comprised LV and BiVdys pts (gender, BSA matched) undergoing echo and CMR within 2 weeks: Echo included standard RV indices (fractional area change [FAC], TAPSE, S’) and linear fractional shortening (FS) in parasternal (RV outflow tract [RVOT]) and apical 4 chamber views (width [RVWD], length [RVLG]). CMR was the reference for volumetric LV & RVdys (EF<50%): Linear echo cutoffs were first established in a derivation cohort; then tested in a validation cohort.
Results: 168 pts (67% M, 57±15 yo) underwent echo and CMR (3±3 days); BiVdys pts had lower RVEF (36±9 vs 58±6%) and LVEF (28±12 vs 37±9%, both p<0.001) on CMR. On echo, FAC (47±9 vs 28±11), TAPSE (1.9±0.4 vs 1.5±0.3) and S’ (11.4±2.3 vs 9.9±2.6, all p<0.001) were lower with BiVdys, as were all linear FS indices (RVOT 32±8 vs 17±10
Author Disclosures: A. Srinivasan: None. J. Kim: None. M. Rusli: None. A. Feher: None. A. Geevarghese: None. A. Di Franco: None. S.A. Khan: None. T. Shah: None. M. Rozenstrauch: None. O. Khalique: None. R.B. Devereux: None. J.W. Weinsaft: None.
- © 2016 by American Heart Association, Inc.