Abstract 12740: Clinical Impact of the Residual Syntax Score in Acute Coronary Syndrome Patients
Introduction: Some studies have shown prognostic value of the residual Syntax score (rSS) in patients with multivessel coronary artery disease. However, it remains unclear that how much impact the rSS has on clinical outcomes in ACS patients.
Hypothesis: A reduction of rSS may relate to the improvement of clinical outcomes in ACS patients.
Methods: This study was an observational study examining consecutive ACS patients from January 2009 to December 2014 at our institution. Study population included 2025 ACS cases. The rSS was derived from post primary and primarily scheduled PCI angiography. Patients were dichotomized into low (<8) and high rSS (≥8) groups and outcomes were compared between groups. The primary outcome of net adverse cardiovascular events (NACE) consisted of a composite of all-cause mortality, non-fatal MI, and any revascularization at 1 year.
Results: The mean rSS was 5.1 (±6.6). The incidence of NACE at 1 year was significantly higher in high rSS group than low rSS group (48.7% versus 26.5%, p<.0001). The incidence of all-cause death (17.4% versus 6.5%, p<.0001) and any revascularization (36.4% versus 21.1%, p<.0001) were also higher in high rSS group. On the other hands, there was no significantly difference between two groups in non-fatal MI (1.9% versus 1.8%, p=.88). After adjustment for confounders, a high rSS was also an independent predictor of the primary outcome with a hazard ratio of 1.94 (95% confidential interval [CI], 1.58-2.39; p<.0001).
Conclusions: Our study suggests that high residual Syntax score (≧8) is significantly associated with poor clinical outcomes.
Author Disclosures: S. Hiramori: None. M. Hyodo: None. Y. Soga: None. S. Shirai: None. K. Ando: None.
- © 2016 by American Heart Association, Inc.