Letter by Venema et al Regarding Article, “Analysis of Workflow and Time to Treatment on Thrombectomy Outcome in the Endovascular Treatment for Small Core and Proximal Occlusion Ischemic Stroke (ESCAPE) Randomized, Controlled Trial”
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To the Editor:
In their article, Menon and colleagues1 confirm the well-known association between time delay and functional outcome after endovascular treatment in acute ischemic stroke.2–3 They show that a short time interval between imaging and reperfusion increased the chance of achieving functional independency but did not find a significant relationship between symptom onset to imaging time and functional outcome.
This finding seems contrary to our belief that every minute delay between onset of stroke and reperfusion, either before or after admission, has a negative effect on functional outcome. One explanation, also suggested by the authors, is the selection …