Response by Nielsen and Lip to Letter Regarding Article, “Should Patients With Atrial Fibrillation and 1 Stroke Risk Factor (CHA2DS2-VASc Score 1 in Men, 2 in Women) Be Anticoagulated? Yes: Even 1 Stroke Risk Factor Confers a Real Risk of Stroke”
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We thank Dr Asinger et al for their comments. On whether or not to provide oral anticoagulant treatment in atrial fibrillation (AF) patients with 1 stroke risk factor, we advocated our viewpoint by using contemporary data from various sources. These data convincingly suggest that AF patients with a CHA2DS2-VASc score 1 (or 2 in women) benefit from oral anticoagulant (OAC) treatment.1
The point made by Dr Asinger of declining stroke rates in AF populations during the past decades are based on selected populations (eg, Framingham- and Medicare-enrolled patients) that might not generalize into a broader unselected nationwide AF patient population. No trend of …