Abstract P182: Role of Obesity for the Risk of Hypertension in Youth
Background: National data on the incidence of and risk factors for pediatric hypertension are scant and the role of obesity during childhood in the development of incident hypertension in children and adolescents is ill-defined.
Study Design: For this population-based cohort of youth in southern California, members of a health plan between 3 and 17 years of age and without hypertension (n = 279,708) were passively followed. Blood pressure (BP) and baseline body mass index were extracted from electronic health records. We classified BP using the definitions of the Fourth Report (NHBPEP 2005).
Results: The cohort was racially/ethnically diverse (52.5% Hispanic, 9.9% Black, 7.4% Asian) and 51.2% were under the age of 12 years. During 1,124,912 person-years of follow-up (over a median of 5.0 years), we identified 9,158 youth with incident hypertension. In analyses adjusted for age and sex, participants who were severely obese had a relative risk (RR) of hypertension of 5.34 (see table) compared to their normal weight counterparts. After additional adjustment for baseline BP (normotensive, single, or repeated medical visits with prehypertension), the association was substantially attenuated (RR of 4.44). When we further adjusted for race/ethnicity and socioeconomic status, the relation was essentially the same.
Conclusions: Severe obesity was a strong predictor of hypertension in children and adolescents. Our study demonstrates a strong, graded and positive relationship between adiposity in youth and hypertension. Strategies aimed at prevention of adiposity in youth may play an important role in the prevention of hypertension.
Author Disclosures: C. Koebnick: None. M.F. Daley: None. Y.D. Mohan: None. K. Reynolds: None. X. Li: None. M.A. Sidell: None. A.H. Porter: None. J. Handler: None. S. Daniels: None. B.D. Kuizon: None.
- © 2016 by American Heart Association, Inc.