Abstract 9923: Feasibility of New Real-Time 3-Dimensional Echocardiographic Imaging in a Mitral Valve Stenosis Model: A Comparison With 2D Imaging
Introduction: This study investigated the feasibility and accuracy of real-time three-dimensional echocardiography (RT3DE) in assessing the severity of simulated mitral stenosis in a pumped porcine heart model.
Hypothesis: RT3DE is accurate for assessing mitral stenosis.
Methods: Eight porcine hearts were used to simulate mitral stenosis. Four different sized inner-diameter tubes (9,11,13 and 15mm) were used to create stenotic mitral valve orifice areas. These tubes were inserted into vinyl tubing which was then connected to a pulsatile pump. A balloon was secured to the end of the tubing entering the left ventricle, and the model was sutured at the mitral annulus. The heart was submerged in a water tank and the pump set at 60 bpm with stroke volumes ranging from 30-70 mL in 10 mL increments. At each increment, images were acquired in 2D echo and RT3DE using a GE Vivid 7 ultrasound system. Data were analyzed using GE EchoPAC PC.
Results: A comparison of true area and measured orifice areas were analyzed for both 2D echo and RT3DE. Linear regression analysis showed excellent correlation 2D and RT3DE acquired areas and true areas (2D: r2=0.9; RT3DE: r2=0.9). It was found that while RT3DE presented significantly similar mean values for all areas tested (P<0.05), 2D-measured areas were consistently larger than expected values (P<0.05).
Conclusions: RT3DE has the potential to be an accurate, noninvasive diagnostic tool in clinical cardiology that overcomes imaging limitations present in 2D echo.
Author Disclosures: K. Gadd: None. L. Tam: None. M. Ashraf: None. H. Lei: None. C. Streiff: None. M. Zhu: None. D.J. Sahn: None.
- © 2015 by American Heart Association, Inc.