Abstract 20045: One in Six South Asian Adults Develop Hypertension Over a Two Year Period: Results From the CARRS Cohort Study
Introduction: Hypertension is a growing public health problem in South Asia. We examined hypertension prevalence, awareness, treatment, and control rates in adult participants at baseline in the CARRS cohort from three large cities in South Asia and report both incidence and predictors of incident hypertension using the longitudinal follow-up data.
Methods: The CARRS Study recruited representative population cohorts of three metropolitan urban cities namely Chennai, Delhi and Karachi. Trained field workers collected socio-demographic and risk factor data from all eligible participants using a structured questionnaire, standardized equipment and a common study protocol. All the participants recruited at baseline were followed-up annually. Fasting blood samples were also collected at baseline and at two year follow-up for biochemical analyses of lipids, glucose and haemoglobin A1c. Blood pressure was recorded at baseline and during annual follow-up visits in the sitting position using electronic sphygmomanometer; two measurements were taken, 5 minutes apart and the mean of two was used for analyses.
Results: In total, 16,287 participants were recruited at baseline (response rate=94.3%) and two year follow-up was completed in 12, 504 participants (response rate=79.2%). Hypertension (JNC-8) was prevalent in one of three men (30.1%, 95% CI: 28.7-31.5) and one of four women (26.8%, 95% CI: 25.7-27.9). Hypertension awareness, treatment and control was alarmingly low (Figure 1). One of six non-hypertensive adults at baseline developed hypertension (80.5 per 1000 person years, 95% CI: 76.3-85.0) over a two year period. Propensity to develop hypertension was higher in older age, men, participants from low socio-economic status, current alcohol users, individuals with overweight, pre-hypertension and dysglycemia.
Conclusion: High incidence and poor awareness of hypertension in South Asian adult population warrants immediate policy attention.
Author Disclosures: P. Jeemon: Employment; Significant; Supported by intermediate fellowship from the Wellcome Trust and Department of Biotechnology, Government of India. S. Ghosh: None. S. Roopa: None. V. Ajay: None. M. Ali: None. M. Deepa: None. V. Mohan: None. M. Kadir: None. N. Tandon: None. K. Narayan: None.
- © 2015 by American Heart Association, Inc.