Abstract 19470: Predicted Impact of Carotid Artery Atherosclerotic Disease for Screening of Abdominal Aortic Aneurysm in Women
Introduction:Screening of abdominal aortic aneurysm (AAA) for women has not been established. The aim of this study was to determine the predictive factors associated with ultrasonographic screening for AAA in patients who receive coronary angiogram (CAG) for suspicion of coronary artery disease (CAD).
Methods: Study patients were consisted with 310 consecutive women over 65 years undergoing initial CAG. Both abdominal and carotid arterial ultrasonography were performed for all patients. Patients with known AAA were excluded in this study. AAA was defined as abdominal aortic diameter ≥30 mm by ultrasonographic examination. Carotid artery atherosclerotic disease (CAAD) was defined as a ≥50% stenosis of internal carotid artery (ICA) in NASCET criteria or ≥150cm/sec of ICA peak systolic velocity. Ankle branch pressure index (ABI) was also performed for all patients, and peripheral arterial disease (PAD) was defined as a ≤0.9 of ABI. CAD was defined as a ≥75% reduction in diameter in at least one major vessel in coronary angiography. Multivariate logistic regression analysis was used to study multiple risk factors (age, hypertension, diabetes, dyslipidemia, smoking, hemodialysis, cerebral infarction, CAD, CAAD and PAD) for AAA.
Results: Of 310 patients, incidental AAA was detected in 10 patients (3.2%) and 1 had AAA diameter of ≥50mm. Patients with CAD included higher prevalence of AAA than those without (5.6% vs 0.7%, P=0.021). Multivariate analysis revealed that age (RR 1.3, 95% CI 1.1 to 1.5, p = 0.001) and CAAD (RR 8.5, 95% CI 1.3 to 55.7, p= 0.025) were significantly associated with a higher prevalence of AAA.
Conclusions: Older age and presence of CAAD should be taken into account as a possible criterion for selective AAA ultrasonographic screening in women over 65 years for suspicion of CAD.
Author Disclosures: Y. Shiratori: None. N. Yokoyama: None. K. Kozuma: None. T. Isshiki: None. Y. Maruyama: None.
- © 2015 by American Heart Association, Inc.