Abstract 19385: Postprandial Hypotension, is it Real? The Preliminary Results of a Pilot Study
Introduction: Postprandial hypotension is an important hemodynamic abnormality but it is very under-recognized. We performed this pilot study to evaluate the prevalence of postprandial hypotension and the possible associations between postprandial blood pressure (BP) decline and other forms of BP variability in type 2 diabetes.
Methods: We enrolled 21 patients with type 2 diabetes. All patients were examined with ambulatory BP monitoring and we recorded every meal time. Postprandial hypotension was defined as a systolic BP fall of at least 20 mmHg compared with baseline BP level.
Results: Mean age was 64.4±11.8 years and 11 patients were female (52.4%). Overall systolic BP and diastolic BP are 127.4±13.2 mmHg and 73.4±9.8 mmHg. Overall systolic BP variability was 13.7±5.5. Average postprandial BP fall was 13.9±10.7 mmHg and the BP fall was most conspicuous after breakfast. Fourteen patients (67%) were experienced postprandial hypotension by definition. Among them, 6 patients (43%) were non-dipper, 5 patients (36%) were reverse dipper and a patient was extreme dipper. Average systolic BP variability was significantly higher in the patients with postprandial hypotension (15.1±6.2 vs. 10.9±1.9, P=0.02).
Conclusions: Postprandial hypotension is common in type 2 diabetes and there is possible relationship between postprandial hypotension and other abnormal BP patterns. To clarify the clinical significance of postprandial hypotension, large sized long term prospective study is needed.
Author Disclosures: J. Lee: None. D. Bae: None. S. Kim: None. S. Lee: None. J. Bae: None. K. Hwang: None. D. Kim: None. M. Cho: None.
- © 2015 by American Heart Association, Inc.