Abstract 17039: Creating Heart Failure-specific Measures From PROMIS®
Background: National policies call for aligning specific treatments with patients’ goals of care. The impact of heart failure (HF) on health status varies among patients. Although several generic and HF-specific patient-reported outcomes tools have been developed, none explicitly address how to combine generic and disease-targeted items in a coherent and interpretable way. Our goal was to develop a HF tool that identifies and integrates condition-specific items with measures from PROMIS®--a system of reliable and precise self-reported health assessment.
Methods: We conducted focus groups with HF patients and semi-structured interviews with HF clinicians. We analyzed the transcribed recordings in Dedoose. Using an iterative process, we conducted a content analysis of interview codes to identify relevant PROMIS® domains and items. Codes that did not map to existing PROMIS® tools were used to define gap areas. New items were drafted to reflect the gap areas and then underwent cognitive testing.
Results: Eight focus groups with a total of 61 patients were conducted. Participants had a mean age of 61, were 39% female, and 90% white. Eleven clinicians (6 MDs, 5 RNs) were interviewed. Sixty-nine items across 12 existing PROMIS® domains were identified. Examples of existing PROMIS® domains were dyspnea, physical function, and depression. Gap analysis and cognitive interviewing produced 22 additional items across 8 domains (3 existing PROMIS® and 5 new domains). The identified new domains were health behavior outcomes, life satisfaction, illness burden, independence, and symptoms.
Conclusions: We developed a specific process for creating a tool that integrates existing PROMIS® domains with disease-specific outcomes important to patients and clinicians. While our process was specific to HF, it may be applied to other high impact health conditions. Next steps include the assessment of the stability, validity, and responsiveness of these via testing in 800 HF patients.
Author Disclosures: F.S. Ahmad: None. K. Kaiser: None. K.E. Schifferdecker: None. A.M. Adachi-Mejia: None. A. Eisenstein: None. G.J. Greene: None. S. Yount: None. D. Cella: None. M. Kallen: None. K.L. Carluzzo: None. E.S. Fisher: None.
- © 2015 by American Heart Association, Inc.