Abstract 17020: Visit-to-visit Variability of Systolic Blood Pressure Predicts All-cause Mortality in Patients Received Percutaneous Coronary Intervention With Drug Eluting Stents
Background: Blood pressure (BP) and its variability are associated with atherosclerotic disease and cardiovascular events. The prognostic implications of outpatient clinic visit-to-visit blood pressure variability (BPV) are unknown in patients received percutaneous coronary intervention (PCI) with drug-eluting stents (DES).
Methods: Patients who PCI from January 2009 to December 2013 were consecutively corrected. We analyzed the 1,234 patients, who measured clinic BP more than three times during follow up. The BPV is determined by standard deviation (SD) of systolic and diastolic BP, and coefficient of variation (SD*100/mean BP).
Results: Median follow up duration was 905 days (interquartile range 529 to 1,310 days). The clinic measured BP were recorded mean 9.9 ± 4.7 times. All patients were divided into two groups according to the coefficient of variation of systolic BP (CVSBP); high CVSBP group (> 8.77, n=617) and low CVSBP group (<8.77, n=617). High CVSBP group had significantly higher all-cause mortality (7.9 versus 3.1%, p<0.001). In multivariate logistic regression analysis for prediction of all-cause mortality after PCI with DES, hazard ratio of high CVSBP group was 2.090 (95% of confidence interval 1.012-4.318, p = 0.046).
Conclusion: The higher visit-to-visit BPV is associated higher mortality in patients performed PCI with DES. The clinic measured visit-to-visit BPV may serve as a predictor of mortality after PCI with DES.
Author Disclosures: S. Seo: None. I. Choi: None. D. Jeon: None. J. Kin: None.
- © 2015 by American Heart Association, Inc.