Abstract 15582: Cardiovascular Risk Factors in Breast Cancer Survivors: Analysis of NHANES 1999-2012
Introduction: There are 2.8 million breast cancer survivors in the U.S. With improved survival from breast cancer, cardiovascular disease has emerged as one of the leading causes of morbidity and mortality. However, few studies have assessed CVD risk factors among breast cancer survivors.
Methods: We analyzed the National Health and Nutrition Examination Survey (NHANES) 1999-2012 to assess CVD risk factors, as defined by AHA/ACC, in adult women with and without a history of breast cancer.
Results: A total of 537 women, age 20 and older, with breast cancer history and 17,902 women without cancer history were included in the analysis. Among women with breast cancer, the mean (SE) age at diagnosis was 56y (0.81). 32.8% had the diagnosis < 5 years; 39.9% survived more than 10 years after diagnosis. Compared to women without cancer, the breast cancer survivors were older (mean age 65 (0.80) vs 46 (0.23)), and more likely to be white (84.2% vs. 67.6%) (both p<0.0001), but with similar education level. In stratified analyses, after adjustment for age, black women with breast cancer compared to black women without cancer history had significantly higher SBP (128.9 vs 124.5, p=0.003), and were more likely to be obese, have hypertension and diabetes (Table). In contrast, there were no significant differences in CVD risk factors in non-black women. There were no differences in lipids profiles between women with and without breast cancer.
Conclusion: CVD risk factors are very prevalent in breast cancer survivors. Improving cardiovascular health through lifestyle change and preventive strategies, particularly in black women with breast cancer, is a public health priority.
Author Disclosures: A. Hassoon: None. L. Appel: None. N. Maruthur: None. H. Yeh: None.
- © 2015 by American Heart Association, Inc.