Abstract 15463: Very Early Tissue Coverage After Drug-eluting Stent Implantation
Introduction: Optical coherence tomography (OCT) have demonstrated neointimal coverage on drug-eluting stents (DES) struts at 6-12 month follow-up. However, there is little information about tissue coverage <30 days after DES implantation.
Methods: OCT was performed in patients who underwent staged percutaneous coronary intervention <30 days (16.3±7.5 days) after DES implantation. Cross-sectional OCT images of DES were analyzed at 1-mm intervals.
Results: A total of 6,054 struts of 29 stents (27 everolimus-eluting stents and 2 zotarolimus-eluting stents) in 24 lesions were analyzed. The stent length was 32.8±9.47 mm, mean stent area 7.50±2.17 mm2, mean lumen area 7.39±2.35 mm2, minimum lumen area 5.69±1.90 mm2, and minimum lumen diameter 2.41±0.39 mm. Stent coverage was observed in 73.5±20.4% of the struts, malapposition 0.85±1.53%, side branch orifice struts 1.37±2.16%, and protruding struts 1.01±4.08%. The tissue thickness was 36.9 ± 14.5 μm. The percentage of stent coverage was significantly lower in the overlapping segments than in the non-overlapping segments (Figure).
Conclusions: Most of DES struts are covered by tissue <30 days after EES implantation. However, the percentage of stent coverage is lower in the overlapping segments.
Author Disclosures: M. Takahara: None. T. Nakayama: None. Y. Fujimoto: None. Y. Kobayashi: None.
- © 2015 by American Heart Association, Inc.