Abstract 14292: Living Heart Human Model: Pacemaker Lead Insertion and Cardiac Cycle Simulation
Introduction: The durability of the pacemaker electrodes is of great importance since damage to them can mean they no longer provide life-saving electrical stimulus. A pacemaker electrode is meant to be a permanent implant, where it is expected to perform for many years without failure. The SIMULIA Living Heart Human Model provides a unique testing environment where a pacemaker electrode can be virtually inserted and mechanically deformed during the cardiac cycle. The virtual nature of the test provides a physiologically accurate methodology to test new and existing devices without exposing patients to un-necessary risk. Further, the computational model allows for hundreds of virtual experiments, where parameters such as lead diameter, stiffness and location are varied to select the design and placement that have optimal reliability
Methods: The SIMULIA Living Heart Human Model is a high-fidelity multiphysics finite element model of a healthy, 4-chamber adult human heart and proximal vasculature. The pacemaker lead was inserted into the right atrium and ventricle through the superior vena cava. The heart model then completes 3 cardiac cycles to determine the deformation of the electrode.
Results: The primary mode of deformation to cause damage is bending; therefore, curvature change of the pacemaker electrode is the output quantity of primary interest. The plot below shows the curvature (left) and maximum alternating curvature (right) along the length of the pacemaker electrode throughout the cardiac cycle.
Conclusions: The results demonstrate the feasibility of utilizing a high-fidelity heart model to estimate the amount of deformation experienced by a pacemaker electrode during the cardiac cycle. This work, coupled with empirical fatigue testing of the implant, will allow for durability calculations to be made of existing and new electrode designs.
Author Disclosures: P. Saraswat: None. K. D'Souza: None. B.P. Baillargeon: None.
- © 2015 by American Heart Association, Inc.