Abstract 14072: Incidence of Stent Thrombosis and Its Predictors After Endovascular Therapy for Femoropopliteal Artery Disease
Background: Stent thrombosis (ST) in the coronary artery has been associated with a high mortality rate (45%). Despite its broad use, incidence of ST and its impact on clinical outcome following endovascular therapy (EVT) for femoropopliteal (FP) lesions have not been systematically studied.
Methods: Five hundred and fifty-nine consecutive patients (74±9 years; 33% female; 47% with critical limb ischemia; 31% TASC C/D) who underwent stent implantation (81% bare metal and 19% drug-eluting stents) in FP lesions (length, 157±100 mm) were retrospectively studied. ST was diagnosed when the following criteria were met: 1) initial procedural success; 2) rapid symptom occurrence; 3) thrombus present at procedure; and 4) lesion resolved with <50% diameter narrowing by thrombolysis. We evaluated the incidence of ST and its impact on major adverse limb event (MALE)-free survival by Kaplan-Meier analysis and by Cox proportional hazard model.
Results: Rate of ST linearly increased during the follow-up and reached 1.6% (7/559) at 36 months following stent implantation. MALE-free survival rate was 74.6% at 36 months after stent implantation. The independent predictors were age (HR), body mass index (HR), CLI (HR), hemodialysis (HR), and chronic heart failure (HR), while ST (0.99; [0.14-7.33] was not significantly associated with MALE-free survival.
Conclusion: ST, which occurred in 1.6% at 36 months after stent implantation, was not an independent predictor of MALE-free survival in patients with PAD in FP lesions.
Author Disclosures: T. Tsujimura: None. O. Iida: None. M. Fujita: None. M. Masuda: None. S. Okamoto: None. K. Nanto: None. T. Kanda: None. T. Shiraki: None. A. Sunaga: None. S. Okuno: None. Y. Matsuda: None. K. Yanaka: None. T. Ohashi: None. M. Uematsu: None.
- © 2015 by American Heart Association, Inc.