Abstract 13871: Heart Transplant Recipients Enjoy Higher Health-related Quality of Life than Left Ventricular Assist Device Recipients
Introduction: The aim of this study was to evaluate and compare health-related quality of life (HRQoL) in patients waiting for heart transplantation (HTx) on inotropic support or on left ventricular assist device (LVAD) support and in patients after HTx.
Methods: A prospective, comparative design was used to characterize changes over time in HRQoL (SF-36) in patients waiting for HTx on inotropic support (Group-Ino: n = 12) or on LVAD support (Group-LVAD: n = 16) and in patients after HTx (Group:HTx: n = 19).
Results: LVAD or HTx free survivals at 1 and 2 years of Group-Ino, Group-LVAD, and Group-HTx were 44% and 33%, 100% and 82%, and 100% and 100%, respectively. Actuarial survivals at 1 and 5 year of the 3 groups were 100% and 89%, 100% and 100%, and 100% and 100%, respectively. The patients on inotropic support stayed hospitalized all through the waiting time, while 31% of patients on LVAD support went back to work or school, and 63% of patients did so after HTx. The SF-36 psychosocial component scores were unexpectedly high in all the 3 groups: 47.9±10.3 in Group-Ino, 51.4±12.5 in Group-LVAD, and 54.5±7.6 in Group-HTx (norm-based scoring, differences not significant among the 3 groups). On the other hand, the SF-36 physical component score was significantly higher in Group-HTx (45.7±11.7) than in Group-Ino (3.9±11.7, p < 0.01) and in Group-LVAD (25.2±18.9, p < 0.01). The changes of treatment status resulted in significant increase in the SF-36 physical component scores: Ino --> LVAD: 16.7±17.2 points, Ino --> HTx: 46.3±12.5 points, LVAD --> HTx: 19.6±28.2 points.
Conclusion: Although the survival after LVAD implantation was as good as that after HTx, HRQoL in HTx recipients was significantly higher than that in LVAD recipients.
Author Disclosures: S. Saito: None. K. Toda: None. T. Nakamura: None. S. Miyagawa: None. Y. Yoshikawa: None. S. Fukushima: None. D. Yoshioka: None. K. Kubota: None. T. Ueno: None. T. Kuratani: None. Y. Sawa: None.
- © 2015 by American Heart Association, Inc.