Abstract 13823: The Cut-off Point and Boundary Values of Waist-to-height Ratio as an Indicator for Cardiovascular Risk Factors in Chinese Adults Population From PURE Study
Objectives: To explore a scientific boundary of WHtR to evaluate central obesity and CVD risk factors in Chinese adult population.
Methods: The data from the Prospective Urban Rural Epidemiology (PURE) China study that carried out during 2005-2007. The final study analytical sample consisted of 43 841 participants (18 019 men and 25 822 women) aged 35-70 years. According to the category of CVD risk factors proposed by Joint National Committee 7 version (JNC7) and the clustering of risk factors, some diagnosis parameters, such as sensitivity, specificity, and receiver operating characteristic (ROC) curve least distance were calculated for hypertension, diabetes, high serum triglyceride (TG), high serum low density lipoprotein cholesterol (LDL-C), low serum high density lipoprotein cholesterol (HDL-C) and clustering of risk factors (number≥2) to evaluate the efficacy each value of WHtR cut-off point. The upper boundary value for severity was fixed on the point whose specificity of the point was gathered more than 90%. And the lower boundary value to indicate over low weight was determined by the percentile distribution of WHtR, at which the 5th percentile (P5) of point, both in male and female population. Then, basis on the principle of convenient and practical for use, determine the optimal boundary values of WHtR for low weight and obvious central obesity.
Results: For the whole study population, the optimal WHtR cut point for CVD risk factors cluster was 0.50.The cut points for severe central obesity were 0.57 in the whole population. The upper boundary values of WHtR to detect risk factors cluster with specificity above 90% were 0.55 and 0.58 for men and women, respectively. Additionally, the cut-off points of WHtR for each of 4 cardiovascular risk factors with specificity above 90% in male ranged from 0.55 to 0.56, while in female ranged from 0.57 to 0.58. The P5of WHtR, which the lower boundary values of WHtR to indicate over low weight, was 0.40 in the whole population.
Conclusion: WHtR 0.50 was an optimal cut point for CVD risks evaluation in Chinese adults population for both genders. The optimal boundaries of WHtR were 0.40 and 0.57 indicating low body weight and severe risk for CVD respectively in Chinese adults.
Author Disclosures: Y. Peng: None. W. Li: None.
- © 2015 by American Heart Association, Inc.