Abstract 12178: Non-contrast T1 Mapping Detects Myocardial Edema in Patients With Takotsubo Cardiomyopathy
Background: Although early gadolinium enhancement (EGE) and T2-weighted image (T2WI) can detect myocardial edema in patients with Takotsubo cardiomyopathy (TCM), the clinical significance of non-contrast T1 mapping remains unclear.
Methods: Cardiac magnetic resonance at 3T was performed in consecutive 11 patients with TCM. Non-contrast T1 mapping using T1 relaxation time was evaluated. The EGE phase was defined as 2 minutes after gadolinium administration.
Results: EGE and high-signal intensity on T2WI were detected at apical ballooning area in all patients (Figure1A, yellow arrows), whereas no late gadolinium enhancement (LGE) was observed. Non-contrast T1 relaxation time in apical region was significantly higher than that in remote myocardium (1510±131 vs. 1291±65 msec, p<0.001) (Figure 1A, green arrows). Non-contrast T1 relaxation time correlated significantly with Extra Cellular Volume (r = 0.793, p = 0.0004) (Figure 1B).
Conclusion: Non-contrast T1 mapping can detect myocardial edema and may differentiate reversible myocardial damage from normal myocardium in TCM.
Author Disclosures: Y. Aikawa: None. T. Noguchi: None. Y. Morita: None. Y. Goto: None. H. Ogawa: None. S. Yasuda: None.
- © 2015 by American Heart Association, Inc.