Abstract 11562: Computational Fluid Dynamics in Type B Aortic Dissection: A Systematic Review
Introduction: Computational fluid dynamics (CFD) has been increasingly used to analyse cardiovascular hemodynamics through simulations to predict the behaviour of blood flow in the cardiovascular system.
Hypothesis: It is hypothesized that CFD modelling assists in clinical decision-making by providing detailed analysis of flow patterns in patients with aortic dissection.
Methods: A search of biomedical database for English literature was performed to identify studies investigating the CFD applications in type B aortic dissection. Only studies dealing with patient’s data were included, while reports based on phantom studies were excluded from the analysis.
Results: Twelve studies were found to meet selection criteria and were included in the analysis. CFD simulations were based on a selected CT or MRI imaging data in 8 studies, while in the remaining four studies, CFD simulations were derived from 3 cases in two studies, and 4 and 8 cases in one study, respectively. CFD models and simulations were found to successfully capture the complex regions of hemodynamic flow by demonstrating low velocities in the false lumen and high velocities in the true lumen. In the true lumen, high time-averaged wall shear stress (TAWSS) was seen in the regions around the tear, while in the false lumen, TAWSS was less uniform due to recirculating flow in the dilated region (Figure). Presence of an additional re-entry tear was shown to provide an extra return path for blood back to the true lumen during systole, and an extra flow path into the false lumen during diastole. Following endovascular stent grafting, large WSS magnitudes were eliminated in the true lumen, while in the false lumen, the maximum WSS was reported to be reduced by more than a factor of 2.
Conclusions: CFD offers insight into the hemodynamic factors such as velocity field and wall shear stress, and CFD models and simulations improve understanding of hemodynamics in type B aortic dissection.
Author Disclosures: Z. Sun: None.
- © 2015 by American Heart Association, Inc.