Abstract O.01: Epidemiology of Kawasaki disease in South Korea, 2009-2011
We assessed the recent epidemiologic features of Kawasaki disease in South Korea from the nationwide survey conducted between 2009 and 2011. We collected data regarding the incidence, symptoms, treatment, and coronary complications associated with acute Kawasaki disease by sending questionnaires to the 100 hospitals that have pediatric residency programs. We received complete responses from 73 hospitals and partial responses from 14 hospitals. A total of 13,031 cases of Kawasaki disease were reported from the 87 hospitals (3,941 in 2009, 4,635 in 2010, and 4,455 in 2011). The male to female ratio was 1.44:1, and the median age at diagnosis was 28 months. From the questionnaires with complete responses, we noted that the incidence of Kawasaki disease per 100,000 children less than 5 years of age was 115.4 in 2009, 132.9 in 2010, and 134.4 in 2011 (average rate, 127.7). Kawasaki disease occurred more frequently during summer (June, July, and August) and during winter (December and January). The recurrence rate was 3.83% (387 of 10,100). The mean total duration of fever was 5.6 ± 2.4 days. The most common symptom was conjunctival injection (88.2%). The standard dose of intravenous immunoglobulin was administered to 93.6% (9,453 of 10,097), and non-responder rate was 11.6%. Coronary aneurysm occurred in 1.9% (180 of 9,028) though giant aneurysm developed in 0.26% (26 of 9,882) of patients over 3 years. Two patients had myocardial infarction. No mortality was reported during this period. In conclusion, the average annual incidence of Kawasaki disease in South Korea has continuously increased to 134.4 per 100,000 children less than 5 years of age in 2011, which is the second highest incidence of Kawasaki disease worldwide, following its incidence in Japan.
Author Disclosures: G. Kim: None. J. Han: None. Y. Park: None. M. Song: None. Y. Hong: None. S. Cha: None. D. Kim: None.
- © 2015 by American Heart Association, Inc.