Abstract P254: Impact of a 12-Weeks Supervised Physical Activity Program After Bariatric Surgery on Cardiorespiratory Capacity; A Randomized Study
Bariatric surgery is an effective long-term treatment for the management of severe obesity. Weight loss induced by bariatric surgery is characterized by a greater reduction in the fat mass than the reduction in muscle mass. Severely obese patients have a reduced exercise-capacity reduced and perform external work with higher energy expenditure. There is a lack of data regarding the effect of physical activity on cardiorespiratory capacity after bariatric surgery. The purpose of this study was to measure the impact of bariatric surgery and the impact of a supervised physical activity program, between months 3 to 6 after bariatric surgery, on cardiorespiratory capacity. Patients were randomized either to a supervised physical activity program group (exercise group) or usual care without personalized physical activity follow-up group (control group). Anthropometric measurements, abdominal and mid-thigh computed tomography scans, heart rate variability (HRV) measurement and maximal exercise test were performed before and at 3 and 6 months after bariatric surgery (sleeve gastrectomy or biliopancreatic diversion with duodenal switch). Patients in the exercise group trained, between 3 to 6 months, at least thrice a week, consisting of 60 minutes of supervised physical activity including aerobic and resistance training. Up to now, 52 patients are enrolled for which so far, 22 patients (13 patients in the exercise group and 9 patients in controls) have completed 6 months follow-up. At baseline, both groups were similar regarding the proportion of women, age, body mass index, maximal oxygen consumption (VO2peak) and for all parameters related to HRV. At 3 months post-operation, the reduction in relative VO2peak (-7.711.1% vs -10.57.5%; exercise vs. control group respectively) and relative oxygen consumption at the anaerobic threshold (-0.122.0% vs 3.641.5%) was similar. VO2peak reduction was determined by the VE/VCO2 slope change (R2=0.25; p=0.05). During the exercise training period, between 3 to 6 months, improvement in VO2peak (22.012.9% vs 20.38.4%) was similar between groups. There was a significant improvement, in the exercise group regarding the anaerobic threshold (10.32.5 to 12.12.9; p<0,001) but no change in maximal heart rate (p=0.58). In the control group, there was a significant increase in maximal heart rate (12926 to 14218; p=0.03) but no change in the anaerobic threshold (p=0.3). Anaerobic threshold improvement, between 3 to 6 months, was determined by the mid-thigh total muscle changes in control (R2=0.97; p=0.002) and parasympathetic activity in the exercise group (R2=0.63; p=0.03). In conclusion, exercise training post-bariatric surgery had favorable impacts on cardiorespiratory capacity. More patients are being studied to further delineate the parameters affected.
Author Disclosures: J. Harvey: None. A. Audrey: None. E. Nadreau: None. A. Sanctuaire: None. S. Marceau: None. L. Biertho: None. S. Biron: None. F. Hould: None. S. Lebel: None. O. Lescelleur: None. P. Poirier: None.
- © 2015 by American Heart Association, Inc.