Abstract P140: Association of Adult Stature With High Blood Pressure and Diabetes: A Cross-Sectional Study in Middle-Aged Mexican Women
Introduction: Evidence from developed countries suggests that adult short stature may be associated with cardiometabolic disease in women. However, this association in low and middle-income settings remains unclear.
Hypothesis: We assessed the hypothesis that stature is inversely associated with diabetes (DM) and high-blood pressure (hBP) in the Mexican setting.
Methods: We conducted a cross-sectional analysis in a sample of 93,481 middle-aged Mexican female teachers, participants of the Mexican Teacher′s Cohort. In 2008 we asked all cohort participants to self report current height following specific measurement instructions. In a validation study we observed a person correlation coefficient of 0.84 between self-report and standardized measurement made by technician. We used a logistic multivariable regression models to estimate the Odds Ratio of self-reported DM or hBP in each stature quintile using the tallest quintile as the reference category.
Results: After adjusting for birth cohort, ethnicity, family history of DM/hBP, birth-weight, occupation of household’s head during childhood, current socioeconomic status (SES) and birthplace, stature was inversely associated with DM, while no association was found with hBP. The odds for DM were 9% higher in the lowest quintile when compared to the upper stature quintile. Stratification for residence resulted in confirmation of these findings only in participants living in urban in contrast to rural environments.
Conclusion: We found an inverse association of stature with DM but not with hBP. Our data suggest that urban setting might be an important effect modifier of this association, which merits further investigation as it might provide us with valuable insights into the epidemiological transition of developing countries.
Author Disclosures: K.P. Puchner: None. E. Ortiz-Panozo: None. I. Vieitez: None. M. Lajous: None. R. Lopez-Ridaura: None.
- © 2015 by American Heart Association, Inc.