Abstract P116: High Depressive Symptoms May Represent a Barrier to Reach Ideal Cardiovascular Health. A Cross-Sectional Analysis in 10 154 Participants From the Paris Prospective Study III
Background: The Ideal Cardiovascular Health is a new tool defined by the American Heart Association with the aim to promote cardiovascular health by assessing 7 modifiable health behaviors and biological risk factors.
Hypothesis: We investigated the hypothesis that high depressive symptoms represent a barrier to reach ideal cardiovascular health. We further explored the relationship of depressive symptoms on the behavioral and biological components of ICVH.
Methods: Between 2008 and 2012, 10 154 men and women 50-75 years of age were examined in a large health center and enrolled in the Paris Prospective Study III. Ideal cardiovascular health comprises 4 behavioral components (nonsmoking, body mass index >18 kg/m2 and <25 kg/m2, physical activity at goal level, and pursuit of an appropriate diet) and 3 biological components (untreated total cholesterol <200 mg/dL, untreated blood pressure <120/80 mmHg, and untreated fasting blood glucose <100 mg/dL). Participants with 0-2, 3-4 and 5-7 ideal health components were categorized as having poor, intermediate and ideal cardiovascular health, respectively. High depressive symptoms were defined as a score >7 on the 13-item Questionnaire of Depression 2nd version, Abridged (QD2A) or the use of antidepressants. Polytomous logistic regression analysis was applied to quantify the association of high depressive symptoms with intermediate and ideal cardiovascular health with poor cardiovascular health used as the reference category. Separate linear regression analyses were performed to examine the relationship of the QD2A scale with the behavioral and the biological cardiovascular health components. Regression models were adjusted for age, sex, living status, educational level and perceived health.
Results: Mean age of participants was 59.1 (SD 6.3) years and 60.2% were males. A total of 851 (8.6%) showed high depressive symptoms, 5.0% in men and 14.2% in women. Poor, intermediate and ideal cardiovascular health was observed in respectively 32.3% (39.9% in men and 20.0% in women), 51.3% (49.7% in men and 54.0% in women) and 16.4% (10.7% in men and 26.0% in women) of study participants. Individuals with high depressive symptoms had a 35% (odds ratio [OR] 0.65; 95% confidence interval [CI] 0.54-0.78) and 43% (OR 0.57; 95% CI 0.44-0.74) decreased chance of having an intermediate and ideal cardiovascular health, respectively. The QD2A scale was significantly associated with the behavioral components β linear regression =-0.38, p<0.001), but not the biological components (β=-0.08, p=0.12). All these results were consistent among men and women.
Conclusion: Participants with high depressive symptoms have a substantially reduced chance of reaching ideal cardiovascular health, especially its behavioral components. High depressive symptoms may represent a barrier to reach ideal cardiovascular health.
Author Disclosures: B. Gaye: None. C. Prugger: None. P. Boutouyrie: None. F. Thomas: None. C. Guibout: None. M.C. Perrier: None. B. Pannier: None. X. Jouven: None. J.P. Empana: None.
- © 2015 by American Heart Association, Inc.