Abstract P039: Dietary Patterns are Associated with Cognitive Function in US Adults
Introduction: As America ages, identifying factors that contribute to the preservation of cognitive function is of growing importance to maintain quality of life in advanced years. Of modifiable risk factors, diet quality has emerged as a promising candidate to impact cognition. Although the Mediterranean diet pattern has been associated with cognitive benefits, few other dietary patterns have been considered.
Hypothesis: We assessed the hypothesis that empirically-derived dietary patterns are associated with cognitive function.
Methods: The REasons for Geographic And Racial Differences in Stroke (REGARDS) study is a national cohort study of 30,239 black and white participants (age > 45). Previously, five dietary patterns (Convenience, Plant-based, Sweets/fats, Southern, and Alcohol/salads) were derived with principal component analysis using data assessed by the Block98 FFQ. Baseline cognitive impairment (a score ≤4) was assessed using the Six-Item Screener. Logistic regression was used to evaluate the odds of baseline cognitive impairment by quintile of dietary pattern adherence.
Results: This analysis included 19,888 participants with complete diet/cognitive data who were free of stroke. After demographic and energy intake adjustments, participants with the highest adherence to the Southern pattern had 37% higher odds of being cognitively impaired at baseline (Q5 vs Q1: OR=1.37; 95% CI: 1.11, 1.69; p for trend: <0.01), while those with the highest adherence to the Alcohol/Salads pattern had 27% lower odds of impairment at baseline (Q5 vs Q1: OR=0.73; 95% CI: 0.61, 0.87; p for trend: <0.01). Addition of covariates resulted in loss of significance but direction of association was similar (Table).
Conclusion: A dietary pattern including salads and alcohol intake was associated with lower odds, and a pattern including fried food and processed meat with higher odds, of baseline cognitive impairment. These associations should be further investigated in relation to preservation of cognitive function over time.
Author Disclosures: K. Pearson: None. V. Wadley: None. L. McClure: None. S. Judd: None.
- © 2015 by American Heart Association, Inc.