Abstract MP94: Impact of a 12-Weeks Supervised Physical Activity Program After Bariatric Surgery on Body Composition and on Abdominal and Mid-Thigh Body Fat Distribution Changes; a Randomized Study
Bariatric surgery is the most effective long-term treatment for the management of severe obesity. Weight loss induced by bariatric surgery is characterize by a greater reduction of fat mass but also by a reduction of muscle mass. So far, there is a lack of data regarding the effect of physical activity after bariatric surgery on changes in weight and muscle mass. The purpose of this study was to measure the impact of supervised physical activity program, between months 3 to 6 after bariatric surgery, on body composition and on abdominal and mid-thigh body fat distribution. Patients were randomized either in a supervised physical activity program group (exercise group) or either usual care without personalized physical activity follow-up group (control group). For all patients, anthropometric measurements (waist circumference and bioimpedance analysis) and computed tomography scan (CT scan) at the abdomen and mid-thigh levels were performed before, at 3 and 6 months after bariatric surgery (sleeve gastrectomy or biliopancreatic diversion with duodenal switch). Patients in the exercise group, were encouraged, between 3 to 6 months, to perform at least 3 times per week, 60 minutes of supervised physical activity including aerobic and resistance training. Up to now, 52 patients are performing this study for which so far, 22 patients (13 patients in exercise group and 9 patients in control group) have completed 6 months follow-up. At baseline, both groups were similar for the proportion of women (54 % vs. 56 %; exercise vs. control group respectively), age (47±12 years vs. 43±15 years), waist circumference (137.5 ±11.1 cm vs. 136.5±8.9 cm), body mass index (45.7±6.6 kg/m2 vs. 43.0±3.8 kg/m2) and for all parameters related to CT scan. At 3 months, post-operative changes were similar between groups except for waist circumference and abdominal subcutaneous adipose tissue which showed a trend (p=0.10) toward a greater reduction in exercise group. During the exercise period, between 3 to 6 months, the reduction was similar between groups for waist circumference (-7.6±5.3 % vs. -8.0±5.1%), weight (-8.9±5.6% vs. -9.2±4.6%) and body fat (-14.1±7.1% vs. -12.7±6.4%). However, there was a trend toward a lower reduction regarding fat-free mass (-0.3±4.2% vs. -2.3±2.0%; p=0.12), mid-thigh total muscle (1.1±4.8% vs. -1.6±3.7%; p=0.19) and mid-thigh fat-infiltrated muscle (-5.6±10.3% vs. -12.9±11.3%; p=0.16) for the exercise group compares to the control group. In conclusion, so far, our complete data in 22 patients suggested a trend toward a favorable impact of exercise regarding a lower decrement in fat-free mass, mid-thigh total muscle and mid-thigh fat-infiltrated muscle in severely obese patients who underwent either sleeve gastrectomy or biliopancreatic diversion with duodenal switch surgery. More patients are being studied to further delineate the effect of supervised physical activity program.
Author Disclosures: A. Auclair: None. J. Harvey: None. A. Sanctuaire: None. S. Marceau: None. L. Biertho: None. S. Biron: None. F. Hould: None. S. Lebel: None. O. Lescelleur: None. P. Poirier: None.
- © 2015 by American Heart Association, Inc.