Abstract 36: Sedentary Behavior and Cardiometabolic Risk Factors Among US Hispanic/Latino Adults: The Hispanic Community Health Study/Study of Latinos (HCHS/SOL)
Background: Sedentary behavior is recognized as a distinct construct that is qualitatively different from lack of physical activity and it has been suggested to be associated with increased risk of cardiometabolic diseases. Data on relationship between objectively measured sedentary behavior and cardiometabolic biomarkers are sparse, especially among US Hispanics/Latinos.
Methods: Sedentary behavior and physical activity were measured using Acticala accelerometers for a 7-day period in 12,443 participants from the Hispanic Community Health Study/Study of Latinos, a population-based study of Hispanics/Latinos aged 18-74 years recruited from randomly selected households in 4 US cities conducted between 2008 and 2011. Participants with at least 10-hour/day of accelerometer wear on at least three days were included in the current analysis. Sedentary behavior was defined as average accelerometer counts per minute <100. Sedentary time was standardized to 16-hour/day of wear time.
Results: The mean sedentary time was 11.9 hours/day (74% of accelerometer wear time). After adjustment for age, gender and other demographic, socioeconomic and lifestyle variables, diastolic blood pressure, LDL-cholesterol, triglycerides, 2-hour glucose, fasting insulin and HOMA-IR increased, while HDL-cholesterol decreased across the quartiles of sedentary time (all P for trend <0.015). Most associations were attenuated but remained significant after further adjustment for BMI and physical activity. Even among individuals meeting physical activity recommendations, sedentary time remained associated with higher levels of diastolic blood pressure, 2-hour glucose, fasting insulin and HOMA-IR (Figure).
Conclusions: Sedentary time is high in US Hispanic/Latino adults and it is associated with an adverse cardiometabolic biomarker profile, independent of physical activity. Our results emphasize the importance of reducing sedentary behavior beyond increasing physical activity in the prevention of cardiometabolic diseases.
Author Disclosures: Q. Qi: None. G. Strizich: None. G. Merchant: None. C. Buelna: None. S.F. Castañeda: None. L.C. Gallo: None. J. Cai: None. M.D. Gellman: None. C. Isasi: None. A.E. Moncrieft: None. L.A.P. Sanchez-Johnsen: None. N. Schneiderman: None. R. Kaplan: None.
- © 2015 by American Heart Association, Inc.