In the article by Yao et al, “Integromic Analysis of Genetic Variation and Gene Expression Identifies Networks for Cardiovascular Disease Phenotypes,” which appeared in the February 10, 2015 issue of the journal (Circulation. 2015;131:536–549. DOI: 10.1161/CIRCULATIONAHA.114.010696), corrections are needed.
In Figure 3, the alternative and reference alleles are switched. For this SNP, the correct reference allele is “A” and the variant allele is “G”.
In the 1st paragraph of page 5, the sentence: “Our sequence analysis revealed that this SNP is an eQTL that regulates expression of FCRL3 by disrupting the Nfkb binding site (Figure 3)” is incorrect. The sentence should read: “Our sequence analysis revealed that this SNP is an eQTL that might be regulating expression of FCRL3 by increasing binding affinity of the Nfkb binding site (Figure 3).”
The corrections have been made to the current online version of the article. The authors sincerely regret the errors.
- © 2015 American Heart Association, Inc.