Abstract 310: Body Mass Index and Initial Defibrillation for In-Hospital Cardiac Arrest
Background: Higher transthoracic impedance may influence the success of defibrillation. We evaluated the relationship between body mass index (BMI) and post-defibrillation outcomes for in-hospital ventricular fibrillation or pulseless ventricular tachycardia (VF/VT).
Methods: Within the Get With The Guidelines - Resuscitation multicenter observational registry, we identified adult patients who received biphasic waveform defibrillation for in-hospital VT/VF cardiac arrest between 2008 and2012. We evaluated the relationship between BMI and defibrillation outcomes using a generalized linear mixed regression to adjust for patient arrest characteristics and comorbidities while accounting for within hospital clustering. The primary outcome was successful termination of VF/VT. Secondary outcomes included termination of VF/VT to an organized rhythm with pulse, return of spontaneous circulation ≥ 20 minutes (ROSC), survival at 24 hours, and survival to discharge.
Results: A total of 10,561 adult subjects with VF/VT from 268 hospitals were analyzed. BMI was not associated with termination of VT/VF following defibrillation. However, compared to normal BMI patients, underweight and morbidly obese patients were less likely to have termination of VT/VF with restoration of a pulse. Further, underweight patients were less likely to survive to 24 hours and discharge. In contrast, overweight and obese patients were more likely to survive to 24 hours and discharge (see Table).
Summary: Successful termination of VF/VT was not associated with BMI. However, a non-linear relationship exists between BMI and termination of VF/VT to an organized rhythm with pulse, ROSC, survival at 24 h and survival at discharge.
Author Disclosures: O. Ogunkua: None. A. Minhajuddin: None. J. Pai: None. G. Joshi: None. C. Whitten: None. E. Babar Melik: None. G. Hill: None. D. Nasir: None. M. Hamza: None. S. Bradley: None. P. Schneider: None. B. Ogunnaike: None.
- © 2014 by American Heart Association, Inc.