Abstract 19957: Why do Patients Participate in Clinical Trials?
Introduction: Participation in clinical trials by patients with cardiovascular disease is paramount to the development of new pharmacological and non-pharmacological treatments. Increased knowledge of what motivates participation to enter into clinical cardiovascular trials may enhance inclusion and retention and minimize lost to follow-up or withdrawal of consent
Methods: We mailed an 11-item questionnaire to 154 patients who were previously or currently participating in one of several clinical cardiovascular trials. We asked patients to score 11 statements from “highly accurate” to “not accurate at all” on a 5-grade scale. In addition, patients were asked to rank the three most important statements regarding their reasons for participation. In addition, data on age, gender, previous disease and other important comorbidities as well as duration of participation were noted by the patients on the form. All questionnaires were anonymized.
Results: 135 patients responded (87%), 78% were men, mean age 68 years. 92% were post-MI patients, 8% post-stroke. The highest score was given to a statement on the importance of continuity of care, followed by statement of altruistic nature i.e. wishing to promote science. The three most important reasons for participation as ranked by the patients were 1: Continuity of care i.e. the opportunity to see the same doctor and nurse at every visit, indicated by 88 patients (65%), followed by wishing to promote science, 73 patients (54)% and 43 patients (32%) indicated that participation in a clinical trial would provide better and more qualified care post MI or post stroke to be an important reason. The least important reason was economic i.e. that visits are free, indicated to be important by only 2 patients.
Conclusions: Patients who participate in clinical trials do so because it may provide access to better and more continuous care but equally important are altruistic motives including a wish to promote science
Author Disclosures: H. Dellborg: None. G. Hultsberg-Olsson: None. M. Dellborg: None.
- © 2014 by American Heart Association, Inc.