Abstract 19756: QTC Intervals Can Be Monitored With the AliveCor Heart Monitor in Patients on Dofetilide for Atrial Fibrillation
Introduction: In patients with persistent atrial fibrillation, dofetilide is an effective means of rhythm control. Recommended routine surveillance of dofetilide therapy includes measurement of the QTC interval every 3 months along with reassessment of kidney function. Such frequent visits can be onerous for patients. The AliveCor heart monitor is a novel smartphone application and tool that permits easily accessible generation of a rhythm strip that is the equivalent of Lead I on a 12-lead ECG. We assessed the feasibility and reliability of AliveCor tracings for QTC assessment in patients undergoing in-hospital dofetilide loading.
Methods: Five consecutive patients with a history of persistent AF were included in this pilot study. The AliveCor tracings were performed in sinus rhythm to facilitate QTC measurements and compared to the QTC on corresponding ECGs performed that same day. All patients had received at least one dose of dofetilide. The standard two-handed measurement was chosen owing to the ease of use by the patients: this creates the equivalent of Lead I. On each AliveCor tracing and ECG, three consecutive QT intervals and their corresponding RR intervals were measured to calculate the average QTC. On the ECG, either Lead II or V5 was used to measure the QT intervals.
Results: An example of one patient’s AliveCor tracing and ECG is shown in the Figure. There was no significant difference between the AliveCor QTC and ECG QTC for any of the 5 patients (all 20msec or less different).
Conclusions: We believe we are reporting the first cases demonstrating that the AliveCor heart monitor can be used to reliably monitor the QTC interval in patients receiving dofetilide. AliveCor may reduce the clinic visit burden for these patients. Our future work will focus on applying this technology to the outpatient setting.
Author Disclosures: K.D. Guise: None. E.H. Chung: None.
- © 2014 by American Heart Association, Inc.