Abstract 19199: A Novel Mobile Phone Delivered Diabetes Prevention Program in Overweight Adults at Risk for Type 2 Diabetes - A Randomized Controlled Trial
Introduction: A moderate amount of weight loss through intensive lifestyle interventions can prevent or delay the onset of type 2 diabetes, but these labor-intensive lifestyle programs are expensive to implement and sustain over longer periods of time. One way to reduce the costs of such programs is to utilize smart phones and mobile apps. The aim of this trial was to assess the feasibility and potential efficacy of a mobile phone delivered diabetes prevention intervention in English-speaking overweight/obese adults at risk for type 2 diabetes.
Methods: In this pilot randomized controlled clinical trial (RCT), 61 adults were randomized to a mobile app plus pedometer intervention (n=30) or pedometer only control (n=31). Mean (±SD) age was 55.2±9.0 years, 77% were women, 48% were racial/ethnic minorities, and baseline body mass index was 33.3±6.0 kg/m2. The content of the intervention curriculum was adapted from the Diabetes Prevention Program, but the frequency of in-person sessions was significantly reduced from 16 to 6 sessions and group exercise sessions were replaced by a home-based exercise program. A mobile phone app developed for this study and a pedometer were used to augment the intervention and provide self-monitoring tools between in-person visits.
Results: Intention-to-treat analyses indicated that intervention group lost an average of 6.2±5.9 kg (-6.8±5.7%) between baseline and 5-month follow-up compared to a gain of 0.3±3.0 kg (0.3±5.7%) in the control group (P<.001). The intervention also resulted in reductions in hip circumference (P<.001) and blood pressure (P<.05), but had no significant effect on lipid or glucose levels. The intervention group had a significant increase in the number of objectively-measured daily steps compared to the control group (P<.001). Both groups reported less saturated fat intake over time, but the intervention group had larger decreases than the control group in saturated fat intake (P<0.05). The intervention and control groups had similar study completion rates (90.3% and 93.3%).
Conclusions: The mobile phone intervention with pedometer use resulted in significantly more weight loss, compared to controls among overweight/obese adults. A full-scale RCT is therefore warranted and feasible.
Author Disclosures: Y. Fukuoka: None. C. Gay: None. K. Joiner: None. E. Vittinghoff: None.
- © 2014 by American Heart Association, Inc.