Abstract 19176: In-hospital Outcomes of Unstable Angina in Patients with Chronic Kidney Disease (CKD) and End Stage Renal Disease (ESRD), Years 2005-2011
Background: Unstable angina (UA) is prevalent in patients with Chronic Kidney Disease (CKD)including End Stage Renal Disease (ESRD) requiring dialysis. Outcomes of UA in these patients are largely unknown. We sought to compare the in-hospital outcomes among the patients with CKD and ESRD admitted with UA.
Methods: We used data from the National Inpatient Sample (NIS) from 2005 to 2011 with the primary discharge diagnosis of UA and the secondary diagnosis of CKD and ESRD. The associations of CKD and ESRD with, in-hospital complications and procedures, discharge outcomes and mortality were explored after adjusting for potential confounders using logistic regression analyses.
Results: Of the 541,948 patients admitted with unstable angina, 17230 (3.17%) had Renal disease (CKD and ESRD). ESRD was present in 4683 (27.18%) patients while 12547 (72.82) patients had CKD. In-hospital complications; deep venous thrombosis (1.4% vs. 0.2%; p<0.002) and sepsis (1.1% vs. 0.1%; p<0.002) were significantly higher in patients with ESRD. Patients with ESRD were more likely to receive cardiac catheterization (18.1% vs. 13.5%; p<0.004). In addition, mean length of stay (3±7 vs. 2±4; P<0.0001) and mean hospital charges ($25734±66994 vs. $18639±50893; P<0.0001) were significantly higher in patients with ESRD compared to the patients with CKD. In-hospital mortality was noted to be significantly higher in patients with ESRD (1.5% versus 0.7%; P<0.03). This relationship remained significant after adjustment for age, gender and potential confounders; odds ratio(OR) 4.2 ,95% confidence interval (CI)= 1.7-10.4, p<0.002.Table 1.
Conclusions: In patients admitted with unstable angina, ESRD status is associated with significantly higher rates of in-hospital complications and mortality in comparison with the other stages of CKD.
Author Disclosures: C.M. Sarwar: None. S. Rijal: None. Y. Akram: None. A.H. Malik: None. M.M. Adil: None. F. Saeed: None.
- © 2014 by American Heart Association, Inc.