Abstract 18953: The Serial Changes of Left Atrial Structure and Function After Catheter Ablation; 1 Year Follow up Study
Introduction: There is a controversy about the improvement of LA function after successful radiofrequency catheter ablation (RFCA), partly because of the difference of LA function assessing modality between studies. Moreover, there is a concern regarding possible LA myocardial damage from ablation procedure itself
Hypothesis: The purpose of this study was to evaluate changing patterns of LA volume and LA function using 2D speckle tracking echocardiography (STE) after ablation and compare the patterns in patients with and without restored sinus rhythm(SR) after RFCA.
Methods: 60 consecutive patients with AF (F/M=27/33, mean age=55.2±9.5 years, paroxysmal=71%) who had taken RFCA were enrolled. Echocardiography with LA deformation images by STE was performed before, 3month, 6month and 1year after RFCA. Patients were divided into 2 groups (Group1; restore of SR, Group2; recurred AF during 1 year follow-up) for analysis.
Results: Group1 was 45 patients (75%) and 15 patients (25%) were Group2. At baseline, LA size was larger and LAEF and LAS were lower in Group2 than that of Group1. During 1 year follow up (FU) period, LAVI became decreased in both groups but was still larger in Group2. In Group1, the improvement of LAEF started from 3 months and steadily increased for 1 year after RFCA. But there was no change of LAS at 3month after RFCA and it was improved at 6 month after RFCA and further increased at 1 year after RFCA. However, in Group2, LAEF and LAS were not changed at each FU periods. (Figure 1).
Conclusions: Reverse structural and functional remodeling ensued from successful RFCA. But the time sequence of reverse remodeling process was differ. Although restoration of SR was achieved by successful RFCA, delayed restoration of LA tissue mechanics was observed.
These finding suggests that until 3-6 months after restoration of SR by RFCA, the patient might not be fully recovered from condition which favor prothrombotic state and development symptoms, like dyspnea.
Author Disclosures: M. Kim: None. S. Kim: None. J. Shim: None. S. Park: None. S. Park: None. Y. Kim: None. W. Shim: None.
- © 2014 by American Heart Association, Inc.