Abstract 17588: Total Atrial Conduction Time Evaluated With Tissue Doppler Imaging Predicts Cardioembolic Stroke in Patients With Acute Ischemic Stroke
Introduction: Cardioembolic stroke has been increased with increasing the prevalence of atrial fibrillation (AF). However, AF cannot be detected in some patients with cardioembolic stroke. Total atrial conduction time is a marker of atrial remodeling and reflects the extent of both electrical and structural remodeling of the atria in contrast to atrial size. Recently, a novel echocardiographic parameter based on tissue Doppler imaging (TDI) has been used to assess the total atrial conduction time. The total atrial conduction time was estimated by measuring the time delay between the onset of the P-wave of electrocardiogram and peak A’-wave on the TDI of the left atrial lateral wall (PA-TDI duration).
Hypothesis: We hypothesized that increased PA-TDI duration is a sensitive predictor for cardioembolic stroke.
Methods: Transthoracic and transesophageal echocardiography were performed at discharge in 59 patients with sinus rhythm (41 males, mean age 69 ± 11 years) who were hospitalized for acute ischemic stroke.
Results: There were 8 patients with cardioembolic stroke. Patients with cardioembolic stroke had higher log BNP, larger left atrial volume index and longer PA-TDI duration (138 ms vs. 119 ms) than those without cardioemboli stroke. Multivariate logistic regression analysis showed that PA-TDI duration was an independent predictor for cardioembolic stroke (odds ratio 3.227 (per 1SD increase), 95% confidence interval 1.156 - 12.228, P<0.05).
Conclusions: PA-TDI duration is a feasible predictor for cardioembolic stroke in patients with sinus rhythm and acute ischemic stroke.
Author Disclosures: G. Yamaura: None. T. Watanabe: None. M. Wanezaki: None. S. Nishiyama: None. S. Sasaki: None. I. Kubota: None.
This research has received full or partial funding support from the American Heart Association
- © 2014 by American Heart Association, Inc.